New VANGUARD Publication: Perspectives from Dutch Healthcare Professionals on the Bioartificial Pancreas

A new VANGUARD article titled “The bio-artificial pancreas to treat type 1 diabetes: Perspectives from healthcare professionals in the Netherlands” has been published in the Journal of Clinical & Translational Endocrinology. This publication is openly accessible online here.

In their research, authors Dide de Jongh, Eline Bunnik, Behiye Ozcan, Robert Zietse, and Emma Massey identified the following key points:
• Recipients will have more mental space to focus on other aspects in life.
• The invisibility of the BAP could enhance the sense of ‘normality’ for recipients.
• Implementing the BAP could lower public healthcare costs.
• There are concerns about safety, inequitable access and relinquishing control.

Abstract

Aims: Healthcare professionals are relevant stakeholders because of their gatekeeper role in the clinic. This study aims to explore their perspectives on the potential future clinical implementation of the bio-artificial pancreas (BAP) for people with type 1 diabetes, and suitable target groups.

Methods: Semi-structured interviews were conducted with 17 healthcare professionals, including endocrinologists, nurses, and pancreas transplant surgeons. Inclusion was stopped once data saturation was reached. The audiotaped interviews were transcribed verbatim. Qualitative content analysis using an inductive approach was conducted to develop themes within a coding framework.

Results: Three main themes emerged: (1) hoped-for benefits, which included improved clinical outcomes, enhanced sense of normality, reduced mental burden for patients and their significant others, greater societal participation, and lower costs; (2) concerns, which included safety and effectiveness, inequitable access, accurate information, control over self-management, and organizational challenges; and (3) allocating the BAP during initial implementation, which included prioritizing people who lack effective treatment options, people with mental health issues, and vulnerable people.

Conclusions: The results of this study are important for researchers and practitioners involved in the development of the BAP, so that they can align its design and the process of clinical implementation with healthcare professionals’ perspectives.