New Generation Cell Therapy:
Bioartificial Pancreas to Cure Type 1 Diabetes

Join us for the final project event

The final project event – VANGUARD Symposium – will take place on Monday, June 30th, 2025, in London, UK, as part of the ESOT Congress 2025. We are thankful to our ESOT partners for making it possible.

Learn more here.

The challenge

Forty million individuals worldwide suffer from type 1 diabetes. This disease is managed by insulin therapy in a vast majority of patients because of the limited accessibility of beta cell replacement therapies.

There is an urgent need for the development of a beta cell replacement therapy that will be available to larger numbers of type 1 diabetic patients.

VANGUARD solution​

The VANGUARD project aims to generate a vascularized and immune-protected bioartificial pancreas that can be transplanted into non-immuno-suppressed patients by combining advanced tissue engineering strategies.

This approach will yield a cell therapy in the form of an Advanced Therapy Medicinal Product (ATMP), which can significantly improve treatment of type 1 diabetes.

Project overview

  • Consortium

    9 partners from 5 countries

  • Budget

    € 6.8 million

  • Duration

    01.01.2020 – 30.06.2025

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