The VANGUARD consortium recently published collaborative work in the journal Transplant International on the generation of pre-vascularised organoids.
The authors from the University of Geneva and the University of Eastern Piedmont show that pre-vascularized islet organoids exhibit enhanced in vitro function compared to native islets, improved engraftment and accelerated vascularization in vivo in a murine model.
The paper is available Open Access on the journal’s website.