VANGUARD publication on Advances and challenges of endocrine pancreas bioengineering available online
A new VANGUARD article has recently been published in Current Opinion in Endocrine and Metabolic Research. “Advances and challenges of endocrine pancreas bioengineering” – Islet transplantation is a valid treatment option for type 1 diabetes patients. Despite the advantages of this intervention, many obstacles limit its efficacy such as the loss of islets during the […]
VANGUARD consortium meeting in Geneva, CH
On June 3-4, the VANGUARD consortium finally met in person after two years of online meetings. The meeting, which took place at the Geneva University Hospital, was an important occasion to discuss the progress of the project and present the latest results of each Work Package. The UNIGE team also conducted a tour of its […]
VANGUARD Ethics Workshop
Bio-artificial organs and bio-engineered or bio-printed tissues for transplantation in humans are rapidly being developed. It is anticipated that some applications will be ready for clinical testing in the near future. How can first-in-human clinical trials be conducted in a safe and responsible manner? What are ethical points to consider for early clinical trials of […]
New publication on the generation of pre-vascularised organoids
The VANGUARD consortium recently published collaborative work in the journal Transplant International on the generation of pre-vascularised organoids. The authors from the University of Geneva and the University of Eastern Piedmont show that pre-vascularized islet organoids exhibit enhanced in vitro function compared to native islets, improved engraftment and accelerated vascularization in vivo in a murine […]
Registration is open for the VANGUARD workshop on ethics in regenerative medicine
Online workshop on the topic of bio-artificial organs and bio-engineered or bio-printed tissues for transplantation in humans that are rapidly being developed.
Research article: Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device
A new VANGUARD research article on Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device has been published in Molecular Therapy, Methods & Clinical Development. The full article can be read online: https://doi.org/10.1016/j.omtm.2021.10.015 Abstract: Hemophilia A (HA) is a rare bleeding disorder caused by deficiency/dysfunction of the FVIII protein. […]
VANGUARD presented at the SFT Congress
Our coordinator Dr Ekaterine Berishvili took a part in the 2021 Société Francophone de Transplantation to share the progress of the VANGUARD project.
VANGUARD researchers awarded at the IPITA 2021 Virtual Congress
IPITA is the international pancreas and islet transplant association and the VANGUARD project had the honour to present its research findings at the 2021 Virtual Congress that took place on 20-23 October.
VANGUARD partners meet for the first time
Representatives from the eight VANGUARD partners travelled from across Europe to Igls in Austria to officially kick-off the project. The meeting took place on the 25th January 2020 and offered all partners the opportunity to get to know each other and their roles within the VANGUARD project in more detail.